Facile Iterative Synthesis of Biphenyl Dendrons with a Functionalized Focus

TitleFacile Iterative Synthesis of Biphenyl Dendrons with a Functionalized Focus
Publication TypeJournal Article
Year of Publication2010
AuthorsWren, Ellen J., Wang Xin, Farlow Anthony, Lo S. C., Burn P. L., and Meredith Paul
JournalOrganic Letters
Volume12
Issue19
Pagination4338-4340
Date Published09/10
AbstractAn iterative procedure gives 1,3,5-phenyl-linked dendrons of up to the fourth generation and enables the formation of different generations of iridium(III) complex-cored dendrimers. The convergent synthesis uses N,N′-1,8-napthyl-3,5-dibromophenylboronamide as the key building block. The iterative synthesis cycle involves deprotection of the boronamide-focused dendron to form a boronic acid and subsequent Suzuki coupling either with the N,N′-1,8-napthyl-3,5-dibromophenylboronamide to give the next dendron generation or with an activated core to form a dendrimer.
URLhttp://pubs.acs.org/doi/abs/10.1021/ol101717c
DOI10.1021/ol101717c